In patients with end-stage renal illness, personal satisfaction is a key determinant of outcome. Therefore, should be regularly assessed in this context assessment reflects only physiological and psychological variables linked with permanent hemodialysis patients in General Hospital Lahore. Data were gathered using a modified questionnaire from Lahore General Hospital, and participants were chosen using a practical technique that included all patients receiving ubiquitous permanent hemodialysis. 110 patients receiving hemodialysis made up the study's sample size. The findings indicate that physiological and psychological variables had a good impact on the quality of life of haemodialysis patients. Work, however, was the most dreadful aspect of quality of life, while the best variables were subjective capability and the type of social collaboration. Additionally, it has been found that factors such as older age, female sexual orientation, poorer socioeconomic level, and higher instructional dimension are linked to lower results.