ARTICLE

NOVEL CROSSLINKING METHODS TO DESIGN HYDROGELS

01 Pages : 1-5

http://dx.doi.org/10.31703/gpsr.2016(I-I).01      10.31703/gpsr.2016(I-I).01      Published : Dec 2016

Novel Crosslinking Methods to Design Hydrogels

    Hydrogels are presently under consideration as matrices for the controlled bioactive molecules delivery particularly proteins and for living cells encapsulation. For these applications, gels must undergo degradation under physiological conditions. This overview summarized and discussed the various physical and chemical crosslinking methods to design hydrogels that are biodegradable. Highly versatile method to prepare hydrogels with good mechanical stability is chemical crosslinking. However, the crosslinker employed can give undesirable reactions with the bioactive substances present in the hydrogel matrix and are often toxic. So, it required to be removed from the gels before application. Physically crosslinked gels can be developed to overcome these adverse effects. Distortion due to variations in environmental conditions like presence of solute particles, ionic strength, pH, temperature and stress are the major disadvantages of reversible gels

    Smoking, Addiction, Bahawalpur community
    (1) Hina Shoukat
    Faculty of Pharmacy & Alternative medicine, The Islamia University of Bahawalpur, Bahawalpur, Punjab, Pakistan.
    (2) Fahad Pervaiz
    Assistant Professor, Faculty of Pharmacy & Alternative medicine, The Islamia University of Bahawalpur, Bahawalpur, Punjab, Pakistan.
    (3) Sobia Noreen
    Faculty of Pharmacy & Alternative medicine, The Islamia University of Bahawalpur, Bahawalpur, Punjab, Pakistan.
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Cite this article

    CHICAGO : Shoukat, Hina, Fahad Pervaiz, and Sobia Noreen. 2016. "Novel Crosslinking Methods to Design Hydrogels." Global Pharmaceutical Sciences Review, I (I): 1-5 doi: 10.31703/gpsr.2016(I-I).01
    HARVARD : SHOUKAT, H., PERVAIZ, F. & NOREEN, S. 2016. Novel Crosslinking Methods to Design Hydrogels. Global Pharmaceutical Sciences Review, I, 1-5.
    MHRA : Shoukat, Hina, Fahad Pervaiz, and Sobia Noreen. 2016. "Novel Crosslinking Methods to Design Hydrogels." Global Pharmaceutical Sciences Review, I: 1-5
    MLA : Shoukat, Hina, Fahad Pervaiz, and Sobia Noreen. "Novel Crosslinking Methods to Design Hydrogels." Global Pharmaceutical Sciences Review, I.I (2016): 1-5 Print.
    OXFORD : Shoukat, Hina, Pervaiz, Fahad, and Noreen, Sobia (2016), "Novel Crosslinking Methods to Design Hydrogels", Global Pharmaceutical Sciences Review, I (I), 1-5
    TURABIAN : Shoukat, Hina, Fahad Pervaiz, and Sobia Noreen. "Novel Crosslinking Methods to Design Hydrogels." Global Pharmaceutical Sciences Review I, no. I (2016): 1-5. https://doi.org/10.31703/gpsr.2016(I-I).01