Medication and Facial Nerve Rehabilitation: A Two-Year Retrospective Analysis of Microsurgical Resection Outcomes for Benign Cerebellopontine Angle Tumors in 31 Cases at Prime Teaching Hospital Peshawar
Microsurgical excision for benign cerebellopontine angle (CP angle) tumors was done retrospectively at Prime Teaching Hospital in Peshawar for two years. With a mean age of 46.5 years, 31 Male patients were observed (68%). In post-operative treatment, the research highlights the need for customized drug regimes and thorough facial nerve rehabilitation. These approaches greatly improved patient outcomes. Nonetheless, persistent effects and variability in recovery highlight how difficult treating CP angle malignancies is. Ultimately, our study aims to improve patient well-being by highlighting the significance of individualized methods and interdisciplinary treatment in neurosurgery.This research aimed to evaluate the results of microsurgical excision for benign tumors of the cerebellopontine angle (CP angle). One of the main goals was to assess the effects of treatment plans and facial nerve rehabilitation on patient recovery. The patient demographics and follow-up period were observed to put the research in perspective.
-
Cerebellopontine Angle Tumors, Microsurgical Resection, Medication Regimens, Facial Nerve Rehabilitation
-
(1) Akram ullah
Assistant Professor, Department of Neurosurgery, Prime Hospital Peshawar, KP, Pakistan.
(2) Naeem ul Haq
Associate Professor, Department of Neurosurgery, Mardan Medical Complex, Mardan, KP, Pakistan.
(3) Mumtaz Ali
Professor, Institute of Neurosciences, Irfan General Hospital, Peshawar, KP, Pakistan.
(4) Bakht-Jehan
Assistant Professor, Department of Neurology, Prime Hospital Peshawar, KP, Pakistan.
(5) Sajid Khan
Assistant Professor, Department of Neurosurgery, Prime Hospital Peshawar, KP, Pakistan.
(6) Muhammad Zubair
Senior Registrar, Department of Neurosurgery, Prime Hospital Peshawar, KP, Pakistan.
- Velho, V., Naik, H., & Guha, A. (2021). Surgical management of cerebellopontine angle epidermoid cysts: an institutional experience of 10 years. British Journal of Neurosurgery, 36(2), 203–212. https://doi.org/10.1080/02688697.2020.1867058
- Franz, L., Marioni, G., Mazzoni, A., De Filippis, C., & Zanoletti, E. (2023). Contemporary Perspectives in Pathophysiology of Facial Nerve Damage in Oto-Neurological and Skull base Surgical Procedures: A Narrative review. Journal of Clinical Medicine, 12(21), 6788. https://doi.org/10.3390/jcm12216788
- Bartusikâ€Aebisher, D., Å»oÅ‚yniak, A., BarnaÅ›, E., Machorowska-Pieniążęk, A., OleÅ›, P., Kawczyk†Krupka, A., & Aebisher, D. (2022). The Use of Photodynamic therapy in the Treatment of Brain Tumors—A Review of the Literature. Molecules, 27(20), 6847. https://doi.org/10.3390/molecules27206847
- Bailo, M., Gagliardi, F., Boari, N., Castellano, A., Spina, A., & Mortini, P. (2019). The role of surgery in meningiomas. Current Treatment Options in Neurology, 21(10). https://doi.org/10.1007/s11940-019-0587-9
- Peters, D. R., Halimi, F., Özduman, K., Levivier, M., Conti, A., Reyns, N., & Tuleasca, C. (2023). Resection of the contrast-enhancing tumor in diffuse gliomas bordering eloquent areas using electrophysiology and 5-ALA fluorescence: evaluation of resection rates and neurological outcome—a systematic review and meta- analysis. Neurosurgical Review, 46(1). https://doi.org/10.1007/s10143-023-02064-7
- Aftahy, A. K., Groll, M., Barz, M., Wagner, A., Lange, N., Butenschön, V. M., Delbridge, C., Bernhardt, D., Meyer, B., & Negwer, C. (2021). Surgical outcome of trigeminal Schwannomas. Cancers, 13(6), 1310. https://doi.org/10.3390/cancers13061310
- Bailo, M., Gagliardi, F., Boari, N., Spina, A., Piloni, M., Castellano, A., & Mortini, P. (2023). Meningioma and other meningeal tumors. In Advances in Experimental Medicine and Biology (pp. 73–97). https://doi.org/10.1007/978-3-031-23705-8_3
- Tokutsu, K., Ito, K., Kawazoe, S., Minami, S., Fujimoto, K., Muramatsu, K., & Matsuda, S. (2023). Clinical characteristics in patients with non-alcoholic steatohepatitis in Japan: a case–control study using a 5-year large-scale claims database. BMJ Open, 13(8), e074851. https://doi.org/10.1136/bmjopen-2023-074851
- Chung, K. C. (2019). Grabb and Smith’s plastic surgery. LWW.
- Sicklick, J. K., Kato, S., Okamura, R., Schwaederlé, M., Hahn, M. E., Williams, C., De, P., Krie, A., Piccioni, D., Miller, V. A., Ross, J. S., Benson, A., Webster, J., Stephens, P. J., Lee, J., Fanta, P. T., Lippman, S. M., Leylandâ€Jones, B., & Kurzrock, R. (2019). Molecular profiling of cancer patients enables personalized combination therapy: the I-PREDICT study. Nature Medicine, 25(5), 744–750. https://doi.org/10.1038/s41591-0019-0407-5
- an Den Bergh, P., Van Doorn, P. A., Hadden, R. D. M., Avau, B., Vankrunkelsven, P., Allen, J. A., Attarian, S., Blomkwist-Markens, P. H., Cornblath, D. R., Eftimov, F., Goedee, H. S., Harbo, T., Kuwabara, S., Lewis, R. A., Lunn, M. P., Nobileâ€Orazio, E., Querol, L., Rajabally, Y. A., Sommer, C., & TopaloÄŸlu, H. (2021). European Academy of Neurology/Peripheral Nerve Society guideline on diagnosis and treatment of chronic inflammatory demyelinating polyradiculoneuropathy: Report of a joint Task https://doi.org/10.1111/ene.14959
- Pfister, S. M., Reyesâ€Múgica, M., Chan, J. K. C., Hasle, H., Lazar, A. J., Rossi, S., Ferrari, A., Jarzembowski, J. A., Pritchardâ€Jones, K., Hill, D. A., Jacques, T. S., Wesseling, P., Terrada, D. H. L., Von Deimling, A., Kratz, C. P., Cree, I. A., & Alaggio, R. (2021). A Summary of the Inaugural WHO Classification of Pediatric Tumors: Transitioning from the Optical into the Molecular Era. Cancer Discovery, 12(2), 331– 355. https://doi.org/10.1158/2159-8290.cd-21-1094
- Hostettler, I. C., Jayashankar, N., Bikis, C., Wanderer, S., Nevzati, E., Karuppiah, R., Waran, V., Kalbermatten, D. F., Mariani, L., Marbacher, S., Guzman, R., Madduri, S., & Roethlisberger, M. (2021). Clinical studies and pre-clinical animal models on facial Nerve preservation, Reconstruction, and regeneration following Cerebellopontine Angle Tumor Surgery–A Systematic Review and Future Perspectives. Frontiers in Bioengineering and Biotechnology, 9. https://doi.org/10.3389/fbioe.2021.65941
- Todorov, A., Kaufmann, F., Arslani, K., Haider, A., Bengs, S., Goliasch, G., Zellweger, N., Tontsch, J., Sutter, R., Buddeberg, B., Hollinger, A., Zemp, E., Kaufmann, M., Siegemund, M., Gebhard, C., & Gebhard, C. E. (2021). Gender differences in the provision of intensive care: a Bayesian approach. Intensive Care Medicine, 47(5), 577–587. https://doi.org/10.1007/s00134-021-06393-3
- Thurin, E. (2021, May 27). Measuring outcomes following brain tumor surgery: a registry based approach. https://gupea.ub.gu.se/handle/2077/68061
- Drabbe, C., Van Der Graaf, W. T., De Rooij, B. H., Grünhagen, D. J., Soomers, V. L. M. N., Van De Sande, M. a. J., Been, L. B., Keymeulen, K., Van Der Geest, I., Van Houdt, W. J., & Husson, O. (2021). The age-related impact of surviving sarcoma on health-related quality of life: data from the SURVSARC study. ESMO Open, 6(1), 100047. https://doi.org/10.1016/j.esmoop.2021.100047
- Busch, T., Brinchmann, E. I., Braeken, J., & Wie, O. B. (2022). Receptive vocabulary of children with bilateral cochlear implants from 3 to 16 years of age. Ear And Hearing, 43(6), 1866– 1880. https://doi.org/10.1097/aud.0000000000001220
- Passias, B. J., Johnson, D., Schuette, H. B., Secic, M., Heilbronner, B., Hyland, S. J., & Sager, A. (2022). Preemptive multimodal analgesia and post-operative pain outcomes in total hip and total knee arthroplasty. Archives of Orthopaedic and Trauma Surgery, 143(5), 2401–2407. https://doi.org/10.1007/s00402-022-04450-0
- Vincent, A. G., Bevans, S. E., Robitschek, J., Wind, G., & Hohman, M. H. (2019). Masseteric-to- Facial nerve transfer and selective neurectomy for rehabilitation of the synkinetic smile. JAMA Facial Plastic Surgery, 21(6), 504–510. https://doi.org/10.1001/jamafacial.2019.0689
- Prachand, V. N., Milner, R., Angelos, P., Posner, M. C., Fung, J. J., Agrawal, N., Jeevanandam, V., & Matthews, J. B. (2020). Medically necessary, Time-Sensitive Procedures: scoring system to ethically and efficiently manage resource scarcity and provider risk during the COVID-19 pandemic. Journal of the American College of Surgeons, 231(2), 281–288. https://doi.org/10.1016/j.jamcollsurg.2020.04. 011
- Serritella, E., Giacomo, P. D., Vompi C, Giordano S, Ferrato, G., & Paolo, C. D. (2019) Acupoints for treating temporomandibular disorders: a literature review. Journal of Osseointegration, 11(2), 224- https://iris.uniroma1.it/handle/11573/1319446
- Stylianou, A., Mpekris, F., Voutouri, C., Papoui, A., Constantinidou, A., Kitiris, E., Kailides, M., & Stylianopoulos, T. (2022). Nanomechanical properties of solid tumors as treatment monitoring biomarkers. Acta Biomaterialia, 154, 324–334. https://doi.org/10.1016/j.actbio.2022.10.021
Cite this article
-
APA : ullah, A., Haq, N. u., & Ali, M. (2023). Medication and Facial Nerve Rehabilitation: A Two-Year Retrospective Analysis of Microsurgical Resection Outcomes for Benign Cerebellopontine Angle Tumors in 31 Cases at Prime Teaching Hospital Peshawar. Global Pharmaceutical Sciences Review, VIII(I), 102-108. https://doi.org/10.31703/gpsr.2023(VIII-I).15
-
CHICAGO : ullah, Akram, Naeem ul Haq, and Mumtaz Ali. 2023. "Medication and Facial Nerve Rehabilitation: A Two-Year Retrospective Analysis of Microsurgical Resection Outcomes for Benign Cerebellopontine Angle Tumors in 31 Cases at Prime Teaching Hospital Peshawar." Global Pharmaceutical Sciences Review, VIII (I): 102-108 doi: 10.31703/gpsr.2023(VIII-I).15
-
HARVARD : ULLAH, A., HAQ, N. U. & ALI, M. 2023. Medication and Facial Nerve Rehabilitation: A Two-Year Retrospective Analysis of Microsurgical Resection Outcomes for Benign Cerebellopontine Angle Tumors in 31 Cases at Prime Teaching Hospital Peshawar. Global Pharmaceutical Sciences Review, VIII, 102-108.
-
MHRA : ullah, Akram, Naeem ul Haq, and Mumtaz Ali. 2023. "Medication and Facial Nerve Rehabilitation: A Two-Year Retrospective Analysis of Microsurgical Resection Outcomes for Benign Cerebellopontine Angle Tumors in 31 Cases at Prime Teaching Hospital Peshawar." Global Pharmaceutical Sciences Review, VIII: 102-108
-
MLA : ullah, Akram, Naeem ul Haq, and Mumtaz Ali. "Medication and Facial Nerve Rehabilitation: A Two-Year Retrospective Analysis of Microsurgical Resection Outcomes for Benign Cerebellopontine Angle Tumors in 31 Cases at Prime Teaching Hospital Peshawar." Global Pharmaceutical Sciences Review, VIII.I (2023): 102-108 Print.
-
OXFORD : ullah, Akram, Haq, Naeem ul, and Ali, Mumtaz (2023), "Medication and Facial Nerve Rehabilitation: A Two-Year Retrospective Analysis of Microsurgical Resection Outcomes for Benign Cerebellopontine Angle Tumors in 31 Cases at Prime Teaching Hospital Peshawar", Global Pharmaceutical Sciences Review, VIII (I), 102-108
-
TURABIAN : ullah, Akram, Naeem ul Haq, and Mumtaz Ali. "Medication and Facial Nerve Rehabilitation: A Two-Year Retrospective Analysis of Microsurgical Resection Outcomes for Benign Cerebellopontine Angle Tumors in 31 Cases at Prime Teaching Hospital Peshawar." Global Pharmaceutical Sciences Review VIII, no. I (2023): 102-108. https://doi.org/10.31703/gpsr.2023(VIII-I).15