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Volume-IX

, Issue-I

(WINTER 2024)

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01 - A Comprehensive Review on Implementation of Quality by Design in Varied Pharmace

http://dx.doi.org/10.31703/gpsr.2024(IX-I).01
10.31703/gpsr.2024(IX-I).01      Published : Mar 2024

Abstract

    This review article investigates how Quality by Design (QbD) ideas are used in different pharmaceutical development processes, such as the creation of analytical methods, formulation optimization, and nanoparticle production. In order to improve product quality, reliability, and regulatory compliance, it covers a variety of studies that use QbD approaches. Critical quality attributes and process v... Details

    Quality by Design, formulation Development, Design Space, Pharmaceuticals.

    (1) Aqsa Qaisar
    Graduate, Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan.
    (2) Maryam Sikandar
    Graduate,Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan.
    (3) Rehan Rustam
    Graduate, Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan.
    (4) Afifa Uppal
    Graduate, Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan.
    (5) Muhammad Adnan
    Graduate, Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan.
    (6) Zahid Ali
    Graduate, Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan.
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02 - Applications and Challenges of CRISPER/Cas-9 System in Cancer Therapy

http://dx.doi.org/10.31703/gpsr.2024(IX-I).02
10.31703/gpsr.2024(IX-I).02      Published : Mar 2024

Abstract

    This review article is aimed at providing an outline of the present information base available on the applications of CRISPR/Cas9 in cancer therapy and the challenges raised by its implementation. We will first explain the mechanism of action and other key components pertaining to the functioning of CRISPR/Cas9 technology. Further, we will provide case studies that have had some success in pre-cli... Details

    Recombinant DNA Technology, CRISPER/Cas-9, Applications, Challenges, Genome, Genome Engineering.

    (1) Ahmad Jalal Masood
    Graduate, Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan.
    (2) Ejaz Ahmed
    Graduate, Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan.
    (3) Rimsha Iftikhar
    Graduate, Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan.
    (4) Laiba Javed
    Graduate, Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan.
    (5) Aimen Sahar
    Graduate, Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan.
    (6) Muhammad Hossain
    Graduate, Department of Pharmacy, Quaid-i-Azam University, Islamabad, Pakistan.
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