ARTICLE

NEUROSURGICAL TREATMENT OF BRAIN TUMORS AN ANALYSIS OF CURRENT STRATEGIES

  1. HOME
  2. ARTICLE

06 Pages : 27-32

http://dx.doi.org/10.31703/gpsr.2023(VIII-II).06      10.31703/gpsr.2023(VIII-II).06      Published : Jun 2023

Neurosurgical Treatment of Brain Tumors: An Analysis of Current Strategies

Abstract

    We have extensively studied the strategies available to many patients admitted to the Neurosurgery Department of the Khyber Teaching Hospital, Peshawar to combat malignant brain diseases. Our survey focused on interviewing leading neurosurgeons, learning about their procedures, and carefully reviewing numerous previous case studies. During our study, a total of sixty cases were observed. We found that craniotomy was the most prevalent method for removing brain tumours, followed by endoscopic surgery and that some patients were sent to specialized clinics for stereotactic and radio surgical procedures. The findings revealed a correlation between tumour type and tumour site, with glioblastoma multiforme and metastatic brain tumours having the greatest rates of morbidity and mortality after surgery. According to the results, craniotomy is the go-to neurosurgical operation for removing brain tumours, and the kind of brain tumour is a crucial determinant in determining the risk of postoperative complications and mortality. The results of this study may have far-reaching consequences for the development of neurosurgical knowledge and technique.

    Neurosurgery, Brain Tumours, Contemporary Techniques, Craniotomy, Endoscopic Surgery, Stereotaxic Surgery, Radiosurgery, Postoperative Morbidity, Mortality

    (1) Muhammad Idris Khan
    Assistant Professor, Neurosurgery Khyber teaching hospital Peshawar, KP, Pakistan.
    (2) Mian Iftikhar Ul Haq
    Assistant Professor, Neurosurgery HMC Peshawar, KP, Pakistan.
    (3) Zahid Khan
    Associate Professor, Neurosurgery LRH Hospital Peshawar, KP, Pakistan.
    (4) Bakth Jamal
    Assistant Professor, Neurosurgery Naseer Uddin Babar Hospital Peshawar, KP, Pakistan.
    (5) Walayat Shah
    Consultant, Neurosurgery DHQ Hospital Mardan, KP, Pakistan.
Fulltext PDF

References

  • Badie, B., Brooks, N. P., & Souweidane, M. M. (2004). Endoscopic and Minimally Invasive Microsurgical Approaches for Treating Brain Tumor Patients. Journal of Neuro-oncology, 69(1–3), 209–219. https://doi.org/10.1023/b:neon.0000041884.93566.fb
  • Belykh, E., Shaffer, K. V., Lin, C., Byvaltsev, V. A., Preul, M. C., & Chen, L. (2020). Blood-Brain Barrier, Blood-Brain Tumor Barrier, and Fluorescence-Guided Neurosurgical Oncology: Delivering Optical Labels to Brain Tumors. Frontiers in Oncology, 10. https://doi.org/10.3389/fonc.2020.00739
  • Campanella, R., Guarnaccia, L., Caroli, M., Zarino, B., Carrabba, G., La Verde, N., Gaudino, C., Rampini, A. D., Luzzi, S., Riboni, L., Locatelli, M., Navone, S. E., & Marfia, G. (2020). Personalized and translational approach for malignant brain tumors in the era of precision medicine: the strategic contribution of an experienced neurosurgery laboratory in a modern neurosurgery and neuro-oncology department. Journal of the Neurological Sciences, 417, 117083. https://doi.org/10.1016/j.jns.2020.117083
  • Djirackor, L., Halldorsson, S., Niehusmann, P., Leske, H., Capper, D., Kuschel, L. P., Pahnke, J., Due-Tønnessen, B. J., Langmoen, I. A., Sandberg, C., Euskirchen, P., & Vik-Mo, E. O. (2021). Intraoperative DNA methylation classification of brain tumors impacts neurosurgical strategy. Neuro-oncology Advances, 3(1), https://doi.org/10.1093/noajnl/vdab149
  • Ebina, K., Andoh, A., Takahashi, T., & Iwabuchi, T. (1990). Development and Clinical Usefulness of a New Neuroendoscope System for CT-guided Stereotactic Brain Surgery. Neurologia Medico- chirurgica, 30(6), 401–407. https://doi.org/10.2176/nmc.30.401
  • Grossman, S. A., & Batara, J. M. F. (2004). Current management of glioblastoma multiforme. Seminars in Oncology, 31(5), 635–644. https://doi.org/10.1053/j.seminoncol.2004.07.005
  • Kalkanis, S. N., Quinones-Hinojosa, A., Buzney, E. A., Ribaudo, H. J., & Black, P. M. (2000). Quality of Life Following Surgery for Intracranial Meningiomas at Brigham and Women’s Hosipital: A Study of 164 Patients Using a Modification of the Functional Assessment of Cancer Therapy–brain Questionnaire. Journal of Neuro-oncology, 48(3), 233–241. https://doi.org/10.1023/a:1006476604338
  • Lehane, D., Bryan, R. M., Horowitz, B., deSantos, L. A., Ehni, G., Zubler, M. A., Moiel, R. H., Rudolph, L., Aldama-Leubbert, A., Mahoney, D. H., & Harper, R. M. (1983). Intraarterial Cis- Platinum Chemotherapy for Patients with Primary and Metastatic Brain Tumors. Cancer Drug Delivery, 1(1), 69–77. https://doi.org/10.1089/cdd.1983.1.69
  • Ma, J., Kim, H., Rim, N., Kim, S. H., & Cho, K. (2010). Differentiation among Glioblastoma Multiforme, Solitary Metastatic Tumor, and Lymphoma Using Whole-Tumor Histogram Analysis of the Normalized Cerebral Blood Volume in Enhancing and Perienhancing Lesions. American Journal of Neuroradiology, 31(9), 1699–1706. https://doi.org/10.3174/ajnr.a2161
  • Muzumdar, D. (2012). Neurosurgery in the Past and Future. An Appraisal. Annals of Medicine and Surgery, 1, 13–15. https://doi.org/10.1016/s2049- 0801(12)70004-3
  • Neska-Matuszewska, M., Bladowska, J., SÄ…siadek, M., & Zimny, A. (2018). Differentiation of glioblastoma multiforme, metastases and primary central nervous system lymphomas using multiparametric perfusion and diffusion MR imaging of a tumor core and a peritumoral zone—Searching for a practical approach. PLOS ONE, 13(1), e0191341. https://doi.org/10.1371/journal.pone.0191341
  • Oya, S., Ikawa, F., Ichihara, N., Wanibuchi, M., Akiyama, Y., Nakatomi, H., Mikuni, N., & Narita, Y. (2021). Nation-wide Brain Tumor Registry- based Study of Intracranial Meningioma in Japan: Analysis of Surgery-related Risks. Neurologia Medico-chirurgica, 61(2), 98–106. https://doi.org/10.2176/nmc.oa.2020-0304
  • Robertson, P. L. (2006). Advances in treatment of pediatric brain tumors. NeuroRx, 3(2), 276– 291. https://doi.org/10.1016/j.nurx.2006.01.001
  • Sheehan, J. P., Niranjan, A., Sheehan, J. M., Jane, J. A., Laws, E. R., Kondziolka, D., Flickinger, J. C., Landolt, A. M., Loeffler, J. S., & Lunsford, L. D. (2005). Stereotactic radiosurgery for pituitary adenomas: an intermediate review of its safety, efficacy, and role in the neurosurgical treatment armamentarium. Journal of Neurosurgery, 102(4), 678–691. https://doi.org/10.3171/jns.2005.102.4.0678
  • Sherman, J. H., Hoes, K., Marcus, J. M., Komotar, R. J., Brennan, C., & Gutin, P. H. (2011). Neurosurgery for Brain Tumors: Update on Recent Technical Advances. Current Neurology and Neuroscience Reports, 11(3), 313–319. https://doi.org/10.1007/s11910-011-0188-9
  • Smith, T. W., Nanney, A. D., Lall, R. R., Graham, R. B., McClendon, J., Lall, R. R., Adel, J. G., Zakarija, A., Cote, D. J., & Chandler, J. P. (2015). Development of venous thromboembolism (VTE) in patients undergoing surgery for brain tumors: Results from a single center over a 10year period. Journal of Clinical Neuroscience, 22(3), 519–525. https://doi.org/10.1016/j.jocn.2014.10.003
  • Turek, G., Pasterski, T., Bankiewicz, K. S., DzierzÄ™cki, S., & ZÄ…bek, M. (2020). Current strategies for the treatment of malignant gliomas – experience of the Department of Neurosurgery, Brodno Masovian Hospital in Warsaw. Polish Journal of Surgery, 92(4), 1–5. https://doi.org/10.5604/01.3001.0014.2473
  • Uche, E. O., Shokunbi, M. T., Malomo, A. O., Akang, E. E., Lagunju, I., & Amanor-Boadu, S. D. (2013). Pediatric brain tumors in Nigeria: clinical profile, management strategies, and outcome. Childs Nervous System, 29(7), 1131–1135. https://doi.org/10.1007/s00381-013-2105-9
  • Walker, D. H., Hamilton, W., Walter, F. M., & Watts, C. (2013). Strategies to accelerate diagnosis of primary brain tumors at the primary–secondary care interface in children and adults. CNS Oncology, 2(5), 447–462. https://doi.org/10.2217/cns.13.36
  • Zhong, Z., Sun, Y., Beidaghi, M., Sun, Q., & Bian, L. (2013). Surgical treatment of brain tumor coexisted with intracranial aneurysm—case series and review of the literature. Neurosurgical Review, 36(4), 645–656. https://doi.org/10.1007/s10143-013-0477-7

Cite this article

APA

    APA : Khan, M. I., Haq, M. I. U., & Khan, Z. (2023). Neurosurgical Treatment of Brain Tumors: An Analysis of Current Strategies. Global Pharmaceutical Sciences Review, VIII(II), 27-32. https://doi.org/10.31703/gpsr.2023(VIII-II).06

CHICAGO

    CHICAGO : Khan, Muhammad Idris, Mian Iftikhar Ul Haq, and Zahid Khan. 2023. "Neurosurgical Treatment of Brain Tumors: An Analysis of Current Strategies." Global Pharmaceutical Sciences Review, VIII (II): 27-32 doi: 10.31703/gpsr.2023(VIII-II).06

HARVARD

    HARVARD : KHAN, M. I., HAQ, M. I. U. & KHAN, Z. 2023. Neurosurgical Treatment of Brain Tumors: An Analysis of Current Strategies. Global Pharmaceutical Sciences Review, VIII, 27-32.

MHRA

    MHRA : Khan, Muhammad Idris, Mian Iftikhar Ul Haq, and Zahid Khan. 2023. "Neurosurgical Treatment of Brain Tumors: An Analysis of Current Strategies." Global Pharmaceutical Sciences Review, VIII: 27-32

MLA

    MLA : Khan, Muhammad Idris, Mian Iftikhar Ul Haq, and Zahid Khan. "Neurosurgical Treatment of Brain Tumors: An Analysis of Current Strategies." Global Pharmaceutical Sciences Review, VIII.II (2023): 27-32 Print.

OXFORD

    OXFORD : Khan, Muhammad Idris, Haq, Mian Iftikhar Ul, and Khan, Zahid (2023), "Neurosurgical Treatment of Brain Tumors: An Analysis of Current Strategies", Global Pharmaceutical Sciences Review, VIII (II), 27-32

TURABIAN

    TURABIAN : Khan, Muhammad Idris, Mian Iftikhar Ul Haq, and Zahid Khan. "Neurosurgical Treatment of Brain Tumors: An Analysis of Current Strategies." Global Pharmaceutical Sciences Review VIII, no. II (2023): 27-32. https://doi.org/10.31703/gpsr.2023(VIII-II).06