Evaluation of the Hypoglycemic Potential of Endophytic Fungi from Leaves Extract of Moringa Oliefera (Pakistan), its Identification and GC-MS Analysis
Crude ethyl acetate extract of endophytic fungi MOL1 and MOL3 of Moringa oliefera was taken to evaluate the hypoglycemic activity in normal and alloxan-induced diabetic rabbits.100mg/kg of MOL1 the values of body weight from 1.42±0.09 decreased to 1.18±0.075 while 200mg/kg of extract reduced body weight from 1.36±0.15 to 1.11±0.132. 100 mg/kg of MOL1 treatment on 15th day showed that the BGL count was decreased from 390.2±10.9 to 200.5±7.65. At a concentration of 200 mg/kg reduced BGL count was 195.5±7.69 from 382.7±15.3. 100mg/kg MOL3 treatment decreased weight to 1.21±0.09 from 1.49±0.08 and 200mg/kg reduced body weight from 1.39±0.18 to 1.11±0.075. In group#4, which received 100 mg/kg body weight of MOL3, the BGL count on the 15th day was 387.4±6.80 and after 1 hour of post-treatment it decreased to 184.4±44.0. MOL3 concentration of 200 mg/kg reduced BGL from 410.4±45.67 to 211.6±33.33 after 3 hours of post-treatment it decreased to 180.3±34.1.
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Ethyl Acetate Extract, Endophytic Fungi, Moringa Oliefera, Hypoglycemic Activity
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(1) Bushra Rehman
Assistant Professor, Rahman Medical Institute, Peshawar, KP, Pakistan.
(2) Sumera Afzal Khan
Associate Professor, Centre of Biotechnology and Microbiology, University of Peshawar, KP, Pakistan.
(3) Hira Ikram
Lecturer, Institute Biotechnology and Microbiology, Bacha Khan University, Charsaddda, KP, Pakistan.
(4) Rabiya Nasir
Assistant Professor, Center of Excellence in Marine Biology, Karachi, Sindh, Pakistan.
(5) Aiman Umar
Assistant Professor, Department of Microbiology, Quaid I Azam University, Islamabad, Pakistan.
Cite this article
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APA : Rehman, B., Khan, S. A., & Ikram, H. (2023). Evaluation of the Hypoglycemic Potential of Endophytic Fungi from Leaves Extract of Moringa Oliefera (Pakistan), its Identification and GC-MS Analysis. Global Pharmaceutical Sciences Review, VIII(I), 109-144. https://doi.org/10.31703/gpsr.2023(VIII-I).16
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CHICAGO : Rehman, Bushra, Sumera Afzal Khan, and Hira Ikram. 2023. "Evaluation of the Hypoglycemic Potential of Endophytic Fungi from Leaves Extract of Moringa Oliefera (Pakistan), its Identification and GC-MS Analysis." Global Pharmaceutical Sciences Review, VIII (I): 109-144 doi: 10.31703/gpsr.2023(VIII-I).16
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HARVARD : REHMAN, B., KHAN, S. A. & IKRAM, H. 2023. Evaluation of the Hypoglycemic Potential of Endophytic Fungi from Leaves Extract of Moringa Oliefera (Pakistan), its Identification and GC-MS Analysis. Global Pharmaceutical Sciences Review, VIII, 109-144.
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MHRA : Rehman, Bushra, Sumera Afzal Khan, and Hira Ikram. 2023. "Evaluation of the Hypoglycemic Potential of Endophytic Fungi from Leaves Extract of Moringa Oliefera (Pakistan), its Identification and GC-MS Analysis." Global Pharmaceutical Sciences Review, VIII: 109-144
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MLA : Rehman, Bushra, Sumera Afzal Khan, and Hira Ikram. "Evaluation of the Hypoglycemic Potential of Endophytic Fungi from Leaves Extract of Moringa Oliefera (Pakistan), its Identification and GC-MS Analysis." Global Pharmaceutical Sciences Review, VIII.I (2023): 109-144 Print.
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OXFORD : Rehman, Bushra, Khan, Sumera Afzal, and Ikram, Hira (2023), "Evaluation of the Hypoglycemic Potential of Endophytic Fungi from Leaves Extract of Moringa Oliefera (Pakistan), its Identification and GC-MS Analysis", Global Pharmaceutical Sciences Review, VIII (I), 109-144
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TURABIAN : Rehman, Bushra, Sumera Afzal Khan, and Hira Ikram. "Evaluation of the Hypoglycemic Potential of Endophytic Fungi from Leaves Extract of Moringa Oliefera (Pakistan), its Identification and GC-MS Analysis." Global Pharmaceutical Sciences Review VIII, no. I (2023): 109-144. https://doi.org/10.31703/gpsr.2023(VIII-I).16