ARTICLE

CHARACTERIZATION AND EVALUATION OF CAPSULES AND STUDY OF QC TESTS FOR CAPSULES

02 Pages : 7-18

http://dx.doi.org/10.31703/gpsr.2018(III-I).02      10.31703/gpsr.2018(III-I).02      Published : Dec 2018

Characterization and Evaluation of Capsules and Study of QC tests for Capsules

    Using the capsule as a dosage form dates back to the early pharmacy days; from those days, the capsule preparation process is greatly evolved in order to meet the current needs of patients and the pharmaceutical industry. Currently, all pharmaceutical industries are making a dynamic change in the specifications of particular dosage forms such as capsules. It has become more difficult to obtain the higher valued drug product from the dosage form, along with the potential for improved delivery that can improve clinical outcomes. In addition, the capsules have played a significant role in drug development because of the hand filling or the production of semiautomatic capsular formulations, which have fewer requirements, and can be developed easily. The article will discuss different tests like Universal tests and specific tests, particularly for capsules, performed prior to the release of the batch to ensure efficacy and safety.

    Capsule, Specifications, Dosage Form, Hand Filling, Semiautomatic Capsular Formulations, Universal Tests and Specific Tests
    (1) Fahad Pervaiz
    Associate Professor, Department of Pharmaceutics, Faculty of Pharmacy, Islamia University Bahawalpur, Bahawalpur, Punjab, Pakistan.
    (2) Sana Ali Zahra
    Undergraduate Student, Department of Pharmacy, Faculty of Biological Sciences, Quaid I Azam University, Islamabad, Pakistan.
    (3) Fariah Qaiser
    Undergraduate Student, Department of Pharmacy, Faculty of Biological Sciences, Quaid I Azam University, Islamabad, Pakistan.
    (4) Syeda Komal Fatima
    Undergraduate Student, Department of Pharmacy, Faculty of Biological Sciences, Quaid I Azam University, Islamabad, Pakistan.
    (5) Rabbia Mazhar Khan
    Undergraduate Student, Department of Pharmacy, Faculty of Biological Sciences, Quaid I Azam University, Islamabad, Pakistan.
  • Banker, G. S., Siepmann, J., & Rhodes, C. (2002). Modern pharmaceutics: CRC Press.
  • Brody, M. S., Schalley, C. A., Rudkevich, D. M., & Rebek, J., Julius & J Angewandte Chemie International Edition. (1999). Synthesis and characterization of a unimolecular capsule. 38(11), 1640-1644.
  • Chang, R. K., Raghavan, K. S., & Hussain, M. A. J. J. o. p. s. (1998). A study on gelatin capsule brittleness: moisture tranfer between the capsule shell and its content. 87(5), 556-558.
  • Chiwele, I., Jones, B. E., Podczeck, F. J. C., & Bulletin, p. (2000). The shell dissolution of various empty hard capsules. 48(7), 951-956.
  • Fatohy, H. A. Course Book Industrial Pharmacy.
  • Galia, E., Nicolaides, E., Hörter, D., Löbenberg, R., Reppas, C., & Dressman, J. J. P. r. (1998). Evaluation of various dissolution media for predicting in vivo performance of class I and II drugs. 15(5), 698-705.
  • Hsieh, D. S. (1994). Drug permeation enhancement- theory and applications. In: Taylor & Francis.
  • Samyn, J. C., & Jung, W. Y. J. J. o. p. s. (1970). In vitro dissolution from several experimental capsule formulations. 59(2), 169-175.
  • Taylor, M. K., Ginsburg, J., Hickey, A. J., & Gheyas, F. J. A. P. (2000). Composite method to quantify powder flow as a screening method in early tablet or capsule formulation development. 1(3), 20-30.
  • Withey, R., & Mainville, C. J. J. o. p. s. (1969). A critical analysis of a capsule dissolution test. 58(9), 1120-1126.

Cite this article

    APA : Pervaiz, F., Zahra, S. A., & Qaiser, F. (2018). Characterization and Evaluation of Capsules and Study of QC tests for Capsules. Global Pharmaceutical Sciences Review, III(I), 7-18. https://doi.org/10.31703/gpsr.2018(III-I).02
    CHICAGO : Pervaiz, Fahad, Sana Ali Zahra, and Fariah Qaiser. 2018. "Characterization and Evaluation of Capsules and Study of QC tests for Capsules." Global Pharmaceutical Sciences Review, III (I): 7-18 doi: 10.31703/gpsr.2018(III-I).02
    HARVARD : PERVAIZ, F., ZAHRA, S. A. & QAISER, F. 2018. Characterization and Evaluation of Capsules and Study of QC tests for Capsules. Global Pharmaceutical Sciences Review, III, 7-18.
    MHRA : Pervaiz, Fahad, Sana Ali Zahra, and Fariah Qaiser. 2018. "Characterization and Evaluation of Capsules and Study of QC tests for Capsules." Global Pharmaceutical Sciences Review, III: 7-18
    MLA : Pervaiz, Fahad, Sana Ali Zahra, and Fariah Qaiser. "Characterization and Evaluation of Capsules and Study of QC tests for Capsules." Global Pharmaceutical Sciences Review, III.I (2018): 7-18 Print.
    OXFORD : Pervaiz, Fahad, Zahra, Sana Ali, and Qaiser, Fariah (2018), "Characterization and Evaluation of Capsules and Study of QC tests for Capsules", Global Pharmaceutical Sciences Review, III (I), 7-18
    TURABIAN : Pervaiz, Fahad, Sana Ali Zahra, and Fariah Qaiser. "Characterization and Evaluation of Capsules and Study of QC tests for Capsules." Global Pharmaceutical Sciences Review III, no. I (2018): 7-18. https://doi.org/10.31703/gpsr.2018(III-I).02